Zygosity analysis service
We offer a robust and cost-effective test for determining the zygosity of a twin pair. The test is based on a panel of 47 extensively validated SNPs and the zygosity is calculated as the likelihood of being monozygotic (identical) versus dizygotic (fraternal) given the genotyping data. The genotyping is performed on MassARRAY Platform from Agena (www.agenabio.com). For further information regarding the validation of the SNP panel and zygosity determination see “Large-scale zygosity testing using single nucleotide polymorphisms” by Hannelius et.al:
Hannelius Ulf; Gherman Loreana; Mäkelä Ville-Veikko; Lindstedt Astrid; Zucchelli Marco; Lagerberg Camilla; Tybring Gunnel; Kere Juha; Lindgren Cecilia M
Large-scale zygosity testing using single nucleotide polymorphisms.
Twin research and human genetics: the official journal of the International Society for Twin Studies 2007;10(4):604-25.